The continuous ink supply system on the Epson R380 printer developed a slow air leak in one cartridge, which may have contributed to the nozzle problems, so I just installed another system from the usual eBay supplier: prefilled with ink and $30 delivered.
As nearly as I can tell, Epson designed a number of features into the R380 specifically to thwart CISS installation, including the awkward bridge across the middle of the printer that interferes with the flat tube feeding ink to the flying cartridges. I managed to route the previous CISS tubing around the bridge, but this time I figured enough was enough.
So I tucked a shop rag inside the printer, put a vacuum cleaner nozzle near the operation, and applied a fine-tooth pull saw to the bridge:
That certainly simplified the rest of the installation…