This should be obvious, but don’t reach across the build platform of your Thing-O-Matic with the extruder at 215 °C: you might bump the nozzle with the back of your hand.

It never really hurt, but the nozzle tip made a nasty punch mark in the middle of a disk of scorched skin.
Ah, you’re not that stupid, are you…
Memo to Self: Gloves?